Skip to content

Assessment of oxytocin concentration during the treatment of chronic pain

Assessment of oxytocin concentration during the treatment of chronic pain - Assessment of oxytocin concentration during the treatment of chronic pain

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000050648
Enrollment
160
Registered
2023-03-22
Start date
2023-05-10
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases that may progress to chronic pain, such as post-stroke central pain or herpes zoster infection

Interventions

We measure salivary and urinary concentrations of oxytocin and norepinephrine after music therapy before the start of treatment for patients who visited our hospital&#39
s pain clinic outpatient with chronic pain or a disease that may transit to chronic pain. As a control group for Intervention 1, music therapy will be administered to healthy volunteers in the same w

Sponsors

Tohoku University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult patients who visit the Tohoku University Hospital Pain Clinic Center with chief complaints of chronic pain associated with post-stroke central pain and herpes zoster.

Exclusion criteria

Exclusion criteria: Substance abuse patients, entry refusal

Design outcomes

Primary

MeasureTime frame
Measure the fluctuation of salivary oxytocin concentration at each phase, such as before the start of treatment, after music therapy, and after pain relief was obtained by various treatments such as oral medication and peripheral nerve block.

Secondary

MeasureTime frame
Compare the concentrations of catecholamines such as noradrenaline and cortisol, alpha amylase, and the pain rating scale in each treatment phase with the above-mentioned oxytocin concentration. As a control group, samples from healthy volunteers before and after music therapy will also be collected to determine whether the changes are due to treatment.

Countries

Japan

Contacts

Public ContactHidehisa Saito

Tohoku University Hospital Department of Operation

hidehisa.saito.e2@tohoku.ac.jp022-717-7321

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026