Head and neck cancer patients
Conditions
Interventions
None listed
Sponsors
Gunma University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) A Malignant tumor in the head and neck region. (2) The lesion is measurable. 3) Radiotherapy is planned. 4) The oral mucosa may be irradiated. 5) The patient is over 18 years of age. 6) Performance Status (PS) is 0-2. (7) The patient has been informed of the name and condition of the disease and is capable of consenting.
Exclusion criteria
Exclusion criteria: 1) Previous radiation therapy to the area to be treated. 2) Active and refractory infection at the irradiated site. (3) Severe complications (uncontrolled diabetes, myocardial infarction, unstable angina, uncontrolled arrhythmia, bleeding tendency, collagen disease requiring steroid administration, etc.). (4) Active multiple cancers (simultaneous multiple cancers and iatrogenic multiple cancers with a disease-free interval of 5 years or less). However, lesions equivalent to intraepithelial or intramucosal carcinoma that are considered curable by local treatment are not included in the active overlapping cancers. (5) Previous surgery in the radiotherapy area. (6) An event occurs during the study period for which radiotherapy should not be initiated. (7) The patient is found not to have a malignant tumor in the head and neck region after the start of the study. (8) If it becomes difficult to continue radiotherapy for some reason after the start of the study. (9) Other medical, psychological, or other factors that make the physician in charge of the patient inappropriate for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To observe the change in oral bacterial flora during radiotherapy and investigate the relationship between the type of specific bacterias and the onset of radiation induced mucositis. | — |
Countries
Japan
Contacts
Public ContactAtsushi Musha
Gunma University Heavy Ion Medical Center
Outcome results
None listed