Older adults with mild cognitive impairment
Conditions
Interventions
Participants will receive a multi-domain intervention program with lifestyle management, exercise instruction, nutritional guidance, cognitive training, and social participation.
Sponsors
National Center for Geriatrics and Gerontology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) aged 65-85 at the time of enrollment 2) have provided a written informed consent on this study by participants.
Exclusion criteria
Exclusion criteria: Subjects who 1) are needed to restrict any physical exercise and/or diet due to functional decline, including presence of bone or joint disease, renal failure, ischemic heart disease, and cardiopulmonary disorders." 2) are diagnosed with dementia. 3) have a MMSE score of less than 21. 4) are unable to speak in Japanese. 5) are unable to perform cognitive tests. 6) have a care-needs certification in the long-term care insurance system. 7) have a history of major depression, bipolar disorder, schizophrenia, or alcohol/drug abuse; current serious or unstable disease. 8) are deemed ineligible for enrollment by the responsible researcher or co-researcher at each institution
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is the proportion of participants who continue to participate in the adapted multi-domain intervention program | — |
Secondary
| Measure | Time frame |
|---|---|
| Program Providers 1. compliance with protocol implementation 2. Acceptability of the intervention 3. Cost of intervention 4. appropriateness of intervention 5. intervention fidelity Program participants 1. acceptability of the intervention 2. disincentives and facilitators for continued participation (questionnaires, interviews) 3. 3. changes in MoCA-J scores from the initial evaluation to the 6-month post-evaluation 4. changes in behavior from the initial evaluation to the 6-month post-evaluation 4. changes in behavior change indices from the initial evaluation to the 6-month follow-up evaluation 5. 5. change in food intake diversity score from the time of the initial evaluation to 6 months 6. change in social participation from the initial assessment to 6 months 7. change in lifestyle from the initial assessment to 6 months 8. 8. change in physical activity from the time of initial assessment to 6 months | — |
Countries
Japan
Contacts
Public ContactYujiro Kuroda
National Center for Geriatrics and Gerontology Department of Prevention and Care Science
Outcome results
None listed