None listed
Conditions
Interventions
Test product was taken once a day for 4 weeks at the prescribed dose (1 capsule) at bedtime.
Placebo product was taken once a day for 4 weeks at the prescribed dose (1 capsule) at bedtime.
Sponsors
KINJIRUSHI Co., Ltd
Kirei Testing Labo Co., Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Japanese healthy female subjects, between 40 years and 50 years old (inclusive) at the time of consent. 2. Subjects whose skin characteristics fall under the skin type III or IV (according to the Fitzpatrick classification). 3. Those who are aware of dry skin.
Exclusion criteria
Exclusion criteria: 1. Subjects with a skin disease such as psoriasis. 2. Subjects with a skin disease such as atopic dermatitis. 3. Subjects taking medications or applying medicines topically that are likely to affect the test results. 4. Subjects with contact allergy or who might exhibit an allergic symptom. 5. Subjects who are undergoing dermatological treatment. 6. Subjects with eczema, rash, sunburn, fleck, or scratch marks on the site of the skin test. 7. Subjects who are pregnant or likely to be, or those who are breast feeding. 8. Subjects who participate in, at the time of initiation of this study, another test that interferes with this study or subjects who are scheduled to attend, during the tests, another test that interferes with this study. 9. Subjects who have tattoos, tattoo stickers, body paints, etc. on the site of the skin test. 10. Subjects who received chemical peel, laser treatment, light irradiation treatment, skin treatment such as injection, or surgery, or beauty therapy on the site of the skin test within 4 weeks by the start of the test. 11. Subjects who are judged as unsuitable by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin hydration in stratum corneum and trans epidermal water loss. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sebum level Skin flexibility (R0) Skin resilience (R7) pH Melanin level Hemoglobin level Multiple peeling Melanin index measured with a color-difference meter Hemoglobin index measured with a color-difference meter Hemoglobin oxygen saturation (HbSO2) measured using a color-difference meter Brightness of skin (L*) measured using a color-difference meter Redness of skin (a*) measured using a color-difference meter Yellowness of skin (b*) measured using a color-difference meter Wrinkles analyzed using a replica image Skin pores analyzed using a replica image Skin texture analyzed using a replica image Spots analyzed using a VISIA UV-induced spots analyzed using a VISIA Brown spots analyzed using a VISIA Wrinkles analyzed using a VISIA Skin texture analyzed using a VISIA Skin pores analyzed using a VISIA Erythema analyzed using a VISIA Porphyrin spots analyzed using a VISIA Body surface temperature Visually assessed dullness Visually assessed spots Visually assessed reddish blur Visually assessed acnes Visually assessed skin pore openings Visually assessed skin pore darkness Visually assessed skin texture mesh roughness Visually assessed wrinkles Visually assessed rough skin Visually assessed resilient skin appearance Visually assessed transparency Questionnaire | — |
Countries
Japan
Contacts
Public ContactDaisuke Aoyagi
KINJIRUSHI Co., Ltd R&D Division
Outcome results
None listed