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Investigation of methods to prevent oocyte degeneration in minimally invasive ICSI

Investigation of methods to prevent oocyte degeneration caused by abnormal rupture in Piezo-assisted intracytoplasmic sperm injection (Piezo-ICSI) - Investigation of methods to prevent oocyte degeneration caused by abnormal rupture in Piezo-ICSI.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000050410
Enrollment
100
Registered
2023-02-22
Start date
2023-02-22
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Inseminated oocytes were classified into the following two groups: normal rupture and abnormal rupture. Among the abnormal rupture groups, the normal fertilization and degeneration rates were compare

Sponsors

Kusuhara Women's Clinic
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1) When semen findings are poor. 2) When the split method is used for the first egg retrieval. 3) When semen findings are good but ICSI is essential due to insemination failure.

Exclusion criteria

Exclusion criteria: 1) When IVF is performed.

Design outcomes

Primary

MeasureTime frame
Normal fertilization rate, degeneration rate, proportion of high-quality embryos on day 3, blastocyst formation, and morphologically high-quality blastocysts—

Countries

Japan

Contacts

Public ContactKohei Mizuno

Kusuhara Women's Clinic Culture department

kusuhara.labo@gmail.com03-6274-6433

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026