Healthy adult female
Conditions
Interventions
Left-right comparison study A group Left side: test article Right side: placebo Each creams are applied twice daily for 12 weeks to the eye corner.
Left-right comparison study B group Left side:
Sponsors
Pias Corporation
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Japanese women aged 50 to 65 at the time of informed consent 2) Subjects who have wrinkles of grade 3 to 5 on the outer corner of the eyes and wrinkle grade left-right difference of 1 or less 3) Subjects who do not have wounds, warts, pimples, or burns around the corners of the eyes that may affect evaluation measurements 4) Subjects who can be removed double eyelid-forming products when during evaluation 5) Subjects who are concerned about wrinkles at the corners of the eyes
Exclusion criteria
Exclusion criteria: 1) Subjects with significantly different wrinkles on the left and right corners of the eyes 2) Subjects with a history of cosmetics allergies 3) Subjects receiving hormone replacement therapy 4) Subjects who have experience of aesthetic medicine that affects the test site 5) Subjects who are currently attending a dermatological clinic 6) Subjects who are pregnant, potentially pregnant, or breastfeeding 7) Subjects who are participating in other clinical trials 8) Subjects who are excessive exposure to ultraviolet rays 9) Subjects who are planning to become pregnant during the test period 10) Subjects who usually use facial equipment 11) Subjects using eye care creams or gels to improve wrinkles
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual evaluation and photographic image evaluation of wrinkle grade at the eye corner Wrinkle replica analysis at eye corner | — |
Secondary
| Measure | Time frame |
|---|---|
| Subjective evaluation by questionnaire | — |
Countries
Japan
Contacts
Public ContactShunya Sahara
Pias Corporation Central R&D Laboratory
Outcome results
None listed