Prediction of motor recovery in postoperative brain tumors using imaging studies

Prediction of motor recovery in postoperative brain tumors using diffusion tensor imaging and regional cerebral blood flow - Prediction of motor recovery in postoperative brain tumors using diffusion tensor imaging and regional cerebral blood flow

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000050336

Enrollment

Registered

2023-02-14

Start date

2016-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain tumors

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 84 patients with supratentorial brain tumors who underwent surgical treatment at Toho University Medical Center Omori Hospital at the period from January 2016 to June 2022, of whom DTI and SPECT could be taken before surgery, included in the study.

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
We evaluated motor function in patients with brain tumors using the Manual Muscle Test (MMT) on admission and at discharge. DTI parameters in the corticospinal tract (CST) (cerebral peduncle, posterior limb of internal capsule, and corona radiata) on the DTI were compared between patients with and without preoperative motor paralysis. The rCBF in the CST on the DTI in both groups was also evaluated in the diseased/healthy and diseased/ipsilateral cerebellar hemispheres. We examined the DTI index of CST on DTI and rCBF in the group with improved postoperative paralysis and the group with unchanged and worsened postoperative paralysis.	—

Measure

Time frame

We evaluated motor function in patients with brain tumors using the Manual Muscle Test (MMT) on admission and at discharge. DTI parameters in the corticospinal tract (CST) (cerebral peduncle, posterior limb of internal capsule, and corona radiata) on the DTI were compared between patients with and without preoperative motor paralysis. The rCBF in the CST on the DTI in both groups was also evaluated in the diseased/healthy and diseased/ipsilateral cerebellar hemispheres. We examined the DTI index of CST on DTI and rCBF in the group with improved postoperative paralysis and the group with unchanged and worsened postoperative paralysis.

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Countries

Japan

Contacts

Public ContactChie Nakada

Toho University Omori Medical Center, Tokyo, Japan Department of Neurosurgery

chie.matsuura@med.toho-u.ac.jp03-3762-4151

Outcome results