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Effect of Cumin Essential Oil (Cuminaldehyde) intake on Cognitive Function in the Elderly: A 12-Week Randomized Controlled Trial

Effect of Cumin Essential Oil (Cuminaldehyde) intake on Cognitive Function in the Elderly: A 12-Week Randomized Controlled Trial - Effects of Cumin Essential Oil Intake on Cognitive Function

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000050328
Enrollment
40
Registered
2024-05-31
Start date
2023-02-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Group that take 25 mg of cumin aldehyde daily Placebo group

Sponsors

University of Tsukuba
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1)Persons between the ages of 65 and 89 at the time the consent form is obtained. (2)Those who do not have a history of diabetes, cerebrovascular disease, cardiovascular disease, cancer, or paralysis (3)Those who can in take cumin essential oil (no allergies or rejection) (4)Those who have no allergy or rejection to gelatin. (5)Those who regularly consume curry powder-based foods daily but can adjust their intake to 2-3 times. (6)Those who have not participated or are not currently participating in any other clinical research within the past 3 months. (7)Those who fully understand the content of this study and are able to commute to the study site on their own.

Exclusion criteria

Exclusion criteria: Subjects with dementia (MMSE<-23 points) and depressions (GDS>-11 points). And/or are taking these medications

Design outcomes

Primary

MeasureTime frame
Cognitive function test

Secondary

MeasureTime frame
Blood concentration of amyloid 1-40 Blood concentration of amyloid 1-42 Brain-derived neurotrophic factor "Trail making peg" test Geriatric Depression Scale Pittsburgh Sleep Quality Index Profile of Mood States 2nd Edition Physical Activity Scale for the Elderly SF8 Health Survey d-ROMs BAP Body composition measured by bioelectrical impedance analysis

Countries

Japan

Contacts

Public ContactTomohiro Okura

University of Tsukuba Faculty of Health and sport science

okura.tomohiro.gp@u.tsukuba.ac.jp+81-29-853-2733

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026