Clinical outcome of patients with calcified nodule detected by Optical coherence tomography after percutaneous coronary intervention

Clinical outcome of patients with calcified nodule detected by Optical coherence tomography after percutaneous coronary intervention - CANDO registry

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000050297

Enrollment

400

Registered

2023-04-01

Start date

2023-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary calcified nodule

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with calcified nodules in the culprit lesion detected by OCT or OFDI 2) Patients treated with DES or DCB 3) Patients over 20 years old 4) Patients with their own consent

Exclusion criteria

Exclusion criteria: 1) patients with life expectancy < 1 year 2) patients with shock status 3) patients with in-stent restenosis or stent thrombosis 4) patients with pregnancy 5) Patients deemed inappropriate for inclusion by the principal investigator or subinvestigator

Design outcomes

Primary

Measure	Time frame
Patient-oriented Composite Endpoint (PoCE) at 12 months after PCI: composite endpoint of all cause death, myocardial infarction and any revascularization Target lesion failure (TLF) at 12 months after PCI: composite endpoint of cardiac death, target vessel-related MI and clinically driven target lesion revascularization (TLR)	—

Secondary

Measure	Time frame
At 12 months after PCI 1) The components of primary outcomes 2) Stent thrombosis 3) Stroke 4) Bleeding event 5) Time to occurrence of each of the primary outcomes At 24 months after PCI 6) The composite endpoint of PoCE 7) The composite endpoint of TLF 8) The components of primary outcomes 9) Stent thrombosis 10) Stroke 11) Bleeding event 12) repeated TLR 13) Time to occurrence of each of the primary outcomes	—

Measure

Time frame

At 12 months after PCI 1) The components of primary outcomes 2) Stent thrombosis 3) Stroke 4) Bleeding event 5) Time to occurrence of each of the primary outcomes At 24 months after PCI 6) The composite endpoint of PoCE 7) The composite endpoint of TLF 8) The components of primary outcomes 9) Stent thrombosis 10) Stroke 11) Bleeding event 12) repeated TLR 13) Time to occurrence of each of the primary outcomes

—

Countries

Japan

Contacts

Public ContactTetsuya Yamamoto

Kobe University Graduate School of Medicine Division of Cardiovascular Medicine, Department of Internal Medicine

m07100ty@jichi.ac.jp078-382-5846

Outcome results