Development of a new adjunctive diagnostic method for Cushing's syndrome

Development of a new adjunctive diagnostic method for Cushing's syndrome - Development of a new adjunctive diagnostic method for Cushing's syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000050256

Enrollment

100

Registered

2023-02-07

Start date

2021-08-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cunshing&#39

Interventions

None listed

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: (1) Patients with adrenal tumor confirmed by abdominal CT and hormone tests (ACTH, cortisol, etc.) at institutions participating in this study (2) Women whose age is 50 years or older (3) Patients diagnosed with Cushing's syndrome or non-functioning adrenal tumor

Exclusion criteria

Exclusion criteria: (1) Patients with highly active malignant tumors (2) Patients taking synthetic steroids (3) Patients with chronic renal failure, chronic heart failure, chronic obstructive pulmonary disease, liver cirrhosis, collagen disease, inflammatory bowel disease, neuromuscular disease, ascites effusion, or scoliosis as comorbid conditions (4) Patients who are heavy drinkers of alcohol or bedridden as their life history (5) Other patients who are deemed inappropriate as research subjects by the investigator.

Design outcomes

Primary

Measure	Time frame
Diagnostic performance of Iliopsoas muscle-visceral fat ratio and PMI for Cushing's syndrome (ROC-AUC, sensitivity, specificity, etc.)	—

Countries

Japan

Contacts

Public ContactTaisuke Uchida

University of Miyazaki Division of Hematology, Diabetes, and Endocrinology, Department of Internal Medicine

taisuke_uchida@med.miyazaki-u.ac.jp0985859121

Outcome results