Evaluation of the effect of polyphenol (hydroxytyrosol) intake on cognitive function in middle-aged and elderly people

Evaluation of the effect of polyphenol (hydroxytyrosol) intake on cognitive function in middle-aged and elderly people - Evaluation of the effect of hydroxytyrosol intake on cognitive function

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000050239

Enrollment

Registered

2023-04-01

Start date

2022-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Pearls rich in Hydroxytyrosol group Olive oil group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Middle-aged and elderly people 2) A person who can go to the place where the experiment is conducted on their own.

Exclusion criteria

Exclusion criteria: 1)A person with paralysis 2)A person who has an allergic reaction to the ingredients of the test food 3)A person who is currently participating in other clinical studies or who have participated within 3 months. 4)A person who is judged by the principal investigator to be inappropriate as the subjects of this study

Design outcomes

Primary

Measure	Time frame
Cognitrax test	—

Secondary

Measure	Time frame
Blood concentrate of amyloid beta 1-40 Blood concentrate of amyloid beta 1-42 Brain-derived neurotrophic factor Trail making peg test Geriatric Depression Scale Pittsburgh Sleep Quality Index JKOM Physical Activity Scale for the Elderly J-CHS Grip strength One-leg balance with eyes open test Timed up and go test 5-m walk test	—

Countries

Japan

Contacts

Public ContactJieun YOON

University of Tsukuba R&D Center for Tailor-Made QOL

yoon.jieunfu@u.tsukuba.ac.jp+81-29-859-1593

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026