Randomized controlled trial comparing intracytoplasmic sperm injection with assisted sperm fusion insemination in patients undergoing micro-insemination

Randomized controlled trial comparing intracytoplasmic sperm injection with assisted sperm fusion insemination in patients undergoing micro-insemination to evaluate efficacy and safety of assisted sperm fusion insemination - ASFI RCT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000050184

Enrollment

Registered

2023-01-31

Start date

2023-01-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

ASFI with sperm bound to zona pellucida of immature or degenerated oocyte Conventional ICSI

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Number of collected oocytes are more than 3. Number of mature oocytes are more than 2. Number of either degenerated or immature oocytes are more than 1. Patients undergoing micro-insemination

Exclusion criteria

Exclusion criteria: Severe oligozoospermia

Design outcomes

Primary

Measure	Time frame
Fertilization rate Degeneration rate Developmental rate to the blastocyst stage	—

Countries

Japan

Contacts

Public ContactShota Hatakeyama

Yanaihara Women's Clinic Laboratory

s.hatakeyama@yanaihara.jp0467-50-0112

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026