Healthy female adults
Conditions
Interventions
Consumption of the test food (four times a day, one drop each) without chewing for six weeks.
Consumption of the placebo food (four times a day, one drop each) without chewing for six weeks.
Sponsors
CPCC Company Limited
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1) Healthy female subjects ranging in age from 35 to 49, at informed consent. (2) Subjects who feel their skin dryness, and the failure of skin elasticity. (3) Subjects who can give informed consent to partake in this study after being provided with an explanation of the protocol detail.
Exclusion criteria
Exclusion criteria: (1) Subjects who take steadily (not less than three times a week) in affecting health-specific/functional (e.g., sodium hyaluronate, glucosylceramide, astaxanthin)/supplementary/health foods. (2) Subjects who have taken affecting medicines (e.g., moisturizer), and have any difficulty in refraining from taking them, during this study. (3) Subjects having a bruise and/or a hurt near the skin-measuring position (buccal region). (4) Subjects having their skin roughness due to pollinosis. (5) Subjects with excessive suntan, or working and playing sports outside for long hours. (6) Subjects planning to travel abroad during this study. (7) Subjects being under a specific care on their face (e.g., facial treatment, body care, electric facial, peeling, laser therapy, and hair removal) at an outside agency. (8) Subjects with excessive alcohol intake. (9) Subjects having a habit of smoking. (10) Subjects having previous/current medical history of severe cardiac, hepatic, renal or digestive diseases. (11) Subjects with pregnancy, possibly one, or lactating. (12) Subjects with drug and food allergy. (13) Subjects suffering from atopic dermatitis, contact one, and cutaneous sensitivity. (14) Subjects being under other clinical tests with medicine or health food, or partook in those within four weeks to this study, or planning to join those after giving informed consent. (15) Subjects who donated over 200 mL of their blood and/or blood components within a month to this study. (16) Subjects who donated their whole blood (400 mL) within the last four months to this study. (17) Subjects who will be collected in total of their blood (800 mL) within the last twelve months, after adding the blood amounts planning to be sampled in this study. (18) Subjects being determined as ineligible for participation, judging from the principal/sub investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin function (stratum corneum moisture-binding capacity, skin viscoelasticity and moisture-evaporating capacity) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Stress Check List 30 2. Visual Analog Scale questionnaire for a mood. 3. State-Trait Anxiety Inventory 4. Questionnaires about skin condition and sleep awareness | — |
Countries
Japan
Contacts
Public ContactMasanori Numa
CPCC Company Limited Clinical Planning Department
Outcome results
None listed