Efficacy of brolucizumab for age-related macular degeneration

One-year outcomes of switching to brolucizumab in nAMD refractory to aflibercept - Efficacy of switching to brolucizumab for wet age-related macular degeneration

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000050137

Enrollment

110

Registered

2023-02-01

Start date

2020-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neovascular age-related macular degeneration

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: nAMD patients refractory to aflibercept

Exclusion criteria

Exclusion criteria: Patients with CNV as a result of high myopia, angioid streaks, hereditary disorders, or uveitis were excluded.

Design outcomes

Primary

Measure	Time frame
Dry macula rate	—

Secondary

Measure	Time frame
The subtype of AMD, best corrected visual acuity, retinal thickness, choroidal thickness, number of treatments, treatment interval, age, sex, medical history (hypertension, diabetes, cerebral infarction, myocardial infarction), smoking history, complications (systemic: cerebral infarction, myocardial infarction, topical: intraocular inflammation, endophthalmitis, rhegmatogenous retinal detachment, cataract)	—

Measure

Time frame

The subtype of AMD, best corrected visual acuity, retinal thickness, choroidal thickness, number of treatments, treatment interval, age, sex, medical history (hypertension, diabetes, cerebral infarction, myocardial infarction), smoking history, complications (systemic: cerebral infarction, myocardial infarction, topical: intraocular inflammation, endophthalmitis, rhegmatogenous retinal detachment, cataract)

—

Countries

Japan

Contacts

Public ContactHiroyuki Kamao

Kawasaki Medical School Department of Ophthalmology

hironeri@med.kawasaki-m.ac.jp0864621111

Outcome results