Contribution of TRP channels on cardiovascular responses to cold pressor test

Contribution of TRP channels on cardiovascular responses to cold pressor test - Contribution of skin thermoreceptor on cardiovascular responses to cold stimulus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000050060

Enrollment

Registered

2023-01-18

Start date

2023-01-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Application of menthol solution to the forearm skin Application of cinnamaldehyde solution to the forearm skin Application of control solution to the forearm skin Application of capsaicine solution to

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: No respiratory or skin diseases, no daily medication and no history of smoking

Exclusion criteria

Exclusion criteria: Have any of the following: respiratory disease, skin disease, or have a history of daily medication and smoking

Design outcomes

Primary

Measure	Time frame
Arterial pressure, pain sensation, autonomic nervous activity	—

Secondary

Measure	Time frame
Heart rate, cardiac output, stroke volume, total peripheral resistance	—

Countries

Japan

Contacts

Public ContactTomomi Fujimoto

Niigata University of Health and Welfare Department of Health and Sports

fujimoto@nuhw.ac.jp0252574675

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026