Prospective Randomized Trial of the Efficacy for Intra-Articular Versus Extra-Articular steroid Injections in Knee Osteoarthritis

Prospective Randomized Trial of the Efficacy for Intra-Articular Versus Extra-Articular steroid Injections in Knee Osteoarthritis - SI study for knee OA

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000050041

Enrollment

Registered

2023-01-17

Start date

2023-01-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Intraarticular steroid injection Extraarticular steroid injection

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria:

Exclusion criteria

Exclusion criteria: 1 Rheumatoid arthritis, multiple arthritis, and other autoimmune disease 2 History of total knee arthroplasty, high tibial osteotomy, and other knee surgery 3 History of intra-articular steroid injection in 6 months 4 In use of opioid analgesics 5 A plan for change of residence or long absence 6 Having difficulty talking Japanese 7 Having difficulty answering to questionnaires for cognitive decline 8 Inappropriate for injection 9 History of hypersensitivity for steroids 10 Person whom principal Investigator or co-Investigator judge to be inappropriate

Design outcomes

Primary

Measure	Time frame
The score of KOOS and NRS after the injection of steroid during 12 weeks	—

Countries

Japan

Contacts

Public ContactHiroshi Watanabe

Nippon Medical School Musashi-Kosugi\x{00a0}Hospital Department of Orthopaedic Surgery

watanabehiroshi@nms.ac.jp044-733-5181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026