Development and validation of prediction models for treatment failure of HFNC in COVID-19: a multicenter cohort study

Development and validation of prediction models for treatment failure of HFNC in COVID-19: a multicenter cohort study - Development and validation of prediction models for treatment failure of HFNC in COVID-19: a multicenter cohort study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000050024

Enrollment

200

Registered

2023-01-13

Start date

2022-06-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients 18 years of age or older with confirmed positive SARS-Cov2 (RT-PCR SARS-Cov2, LAMP method, antigen test) who were hospitalized and treated with HFNT. (2) No more criteria for starting HFNT.

Exclusion criteria

Exclusion criteria: Patients under 18 years of age Patients who used non-invasive positive pressure ventilation (NIV) prior to the use of HFNT Patients with Do not Intubation Use after extubation

Design outcomes

Primary

Measure	Time frame
Failure of treatment (intubation or death within 1 week, transition to noninvasive positive pressure ventilation)	—

Secondary

Measure	Time frame
Death within 1 week, intubation within 1 week, transition to noninvasive positive pressure ventilation, and Clinicallyy important intubation	—

Countries

Japan

Contacts

Public ContactDaisuke Irimada

Graduate School of Medicine, Tohoku University Anesthesiology and Perioperative Medicine

daisukeirimada78@yahoo.ne.jp022-717-7321

Outcome results