Evaluation of D-aspartic acid, Zinc and Co-enzyme Q 10 supplementation on different semen parameters in idiopathic male infertility: a randomized double blind placebo controlled study

Evaluation of D-aspartic acid, Zinc and Co-enzyme Q 10 supplementation on different semen parameters in idiopathic male infertility: a randomized double blind placebo controlled study - Evaluation of D-aspartic acid, Zinc and Co-enzyme Q 10 supplementation on different semen parameters in idiopathic male infertility: a randomized double blind placebo controlled study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000050023

Enrollment

100

Registered

2023-02-14

Start date

2023-03-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

male infertility

Interventions

Group A will d-aspartic acid daily for 3 months Group B will receive placebo daily for 3 months

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Any infertile male aged 25 to 40 years old suffering from idiopathic infertility will be included

Exclusion criteria

Exclusion criteria: Any idiopathic infertile male suffering from varicocele or leukocytospermia or immunological infertility will be excluded. Finally, any infertile patient with small testicular volume < 8 ml will be also excluded

Design outcomes

Primary

Measure	Time frame
improvement of different semen parameters	—

Secondary

Measure	Time frame
change in free testosterone level	—

Countries

Africa

Contacts

Public ContactSameh GamalEl Din

Cairo university Andrology

samehfayek@kasralainy.edu.eg01227109309

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026