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Randomized Controlled Trial of preserving vs resecting residual stomach for Esophageal Cancer after Distal Gastrectomy

Randomized Controlled Trial of preserving vs resecting residual stomach for Esophageal Cancer after Distal Gastrectomy - RCT of preserving vs resecting residual stomach for EC after DG

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000049944
Enrollment
80
Registered
2023-01-01
Start date
2023-02-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

preserving residual stomach resecting residual stomach

Sponsors

Osaka university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Esophageal cancer diagnosed as squamous cell carcinoma, adenosquamous carcinoma, carcinosarcoma, basaloid carcinoma, or adenocarcinoma on biopsy Patients who have undergone distal gastrectomy (B-I reconstruction) for gastric cancer, gastric ulcer, duodenal ulcer, etc. Patients who are judged to be eligible for sternal jejunum or sternal colon reconstruction in preoperative estimation. Performance status 0-2 (ECOG classification) Patients diagnosed as eligible for R0 resection Patients with written consent to participate in this study No previous surgery involving resection of jejunum Patients with adequate bone marrow, liver, and renal function

Exclusion criteria

Exclusion criteria: Cases with preoperative examination showing non-curative factors such as dissemination, liver metastasis, distant metastasis, etc. Cases of concurrent overlapping cancers Heterochronic overlapping cancers that have recurred after treatment or have been untreated for more than 5 years, or are currently carcinoma-bearing other than gastric cancer. Patients with poorly controlled diabetes mellitus (HbA1c: 8.0 or higher). Patients deemed by the investigator to be inappropriate for the safe conduct of this study.

Design outcomes

Primary

MeasureTime frame
Weight loss at 6 months after surgery

Countries

Japan

Contacts

Public ContactKoji Tanaka

Osaka university Department of Gastroenterological Surgery, Graduate School of Medicine

ktanaka@gesurg.med.osaka-u.ac.jp0668793251

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026