acute uncomplicated cystitis
Conditions
Interventions
Cephalexin continuous formulation 500 mg (potency) twice daily for 7 days.
Sponsors
Sapporo Medical University School of Medicine
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Patients with subjective symptoms of urinary pain, frequency, urinary urgency, and lower abdominal pain. However, patients with no symptoms of cystitis within 4 weeks prior to the current onset. Pyuria Patients whose pyuria prior to initiation of medication meets any of the following criteria Urine occult blood test by non-centrifugal urine 10 WBCs/hpf or greater Urine detector method with non-centrifuged urine positive Urine sediment sample positive 5 WBCs/hpf or greater
Exclusion criteria
Exclusion criteria: 1) Patients who received other antimicrobial agents prior to the start of study drug and whose symptoms are already improving. 2) Patients who have received a cephalosporin antibiotic within 1 week prior to the start of study drug administration 3) Patients with severe infections that are not expected to respond to oral therapy 4) Patients with serious underlying diseases or complications that make it difficult to evaluate the efficacy and safety of the study drug 5) Patients with a history of allergy to cephalosporins 6) Patients with severe cardiac or hepatic dysfunction 7) Patients with moderate or severe renal dysfunction (serum creatinine level should be 2 mg/dL or higher) 8) Patients with epilepsy or other convulsive disorders or a history of such disorders 9) Pregnant women, women who may be pregnant, and lactating women 10) Other patients deemed inappropriate by the attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary efficacy from the end of the medication to 10 days after the end of the medication | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety | — |
Countries
Japan
Contacts
Public ContactMitsuru yasuda
Sapporo Medical University School of Medicine Department of Infection Control & Laboratory Medicine
Outcome results
None listed