Effects of Light Stimulation of Melanopsin Retinal Ganglion Cells on Pupil Diameter in Humans Based on Silent Substitution Method

Effects of Light Stimulation of Melanopsin Retinal Ganglion Cells on Pupil Diameter in Humans Based on Silent Substitution Method - Effects of Light Stimulation of Melanopsin Retinal Ganglion Cells on Pupil Diameter in Humans Based on Silent Substitution Method

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000049874

Enrollment

Registered

2022-12-22

Start date

2022-12-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Light with different control methods (silent-substitution method, background contrast method, frequency modulation method)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Since the purpose is to collect basic data, the study will be conducted with adults, not the elderly.

Exclusion criteria

Exclusion criteria: Patients with a result score of 3 or 4 on the Cornell Medical Index for neurosis emotional disorders Extreme morning person or extreme night person in Mornings Eveningness Questionnaire Pittsburgh Sleep Questionnaire with a score of 6 or higher Those who have had a change in their living hours due to shift work or travel to time zones within one month Those who are taking any oral medication or smoking Students who are currently enrolled or may be enrolled in a course that the principal investigator is taking

Design outcomes

Primary

Measure	Time frame
pupil diameter	—

Countries

Japan

Contacts

Public ContactTomoko Wakamura

Kyoto University Human Health Sciences, Graduate School of Medicine

wakamura.tomoko.5v@kyoto-u.ac.jp81-75-751-3974

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026