Atopic Dermatitis
Conditions
Interventions
Corectim group Colectim ointment twice a day, but Lidomex ointment can be used in case of eczema exacerbation.
Steroid group Lidomex ointment twice daily, if eczema improves, patients may be switche
Sponsors
National Hospital Organization Sagamihara National Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Pediatric patients with atopic dermatitis who have eczema on the elbow fossa with vIGA-AD score of 2 or higher
Exclusion criteria
Exclusion criteria: (1) Patients with a history of use of group II or higher topical steroids or delgocitinib ointment on the forearm within 1 month (2) Patients with signs of infection on the forearm (3) Patients with a history of use of biological drugs within 1 year or who are going to use biological drugs during participation in the study (4) Other patients deemed inappropriate as research subjects by the principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in TEWL and SCH from baseline to 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in TARC, SCCA2, EASI, pEASI and vIGA from baseline to 12 weeks TEWL, SCH, and questionnaire scores for eczematous and non-eczematous areas at 12 weeks TARC, SCCA2, EASI, pEASI and vIGA at 12 weeks EIS results at baseline and at 12 weeks, and findings from tape stripping | — |
Countries
Japan
Contacts
Public ContactAkira Kawai
National Hospital Organization Sagamihara National Hospital Department of pediatrics
Outcome results
None listed