Prospective interventional study comparing the use of 230 mmHg tourniquet pressure versus 280 mmHg in total knee arthroplasty.

Prospective interventional study comparing the use of 230 mmHg tourniquet pressure versus 280 mmHg in total knee arthroplasty. - Prospective interventional study comparing the use of 230 mmHg tourniquet pressure versus 280 mmHg in total knee arthroplasty.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000049800

Enrollment

120

Registered

2022-12-16

Start date

2022-12-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

kenn osteoarthritis

Interventions

Intervene the pressure of the tourniquet used during total knee arthroplasty. The patients will be divided into two groups: one using a pressure of 230 mmHg. the other using a pressure of 280 mmHg

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with primary knee osteoarthritis who underwent a TKA.

Exclusion criteria

Exclusion criteria: Patients with a history of venous thromboembolism,bleeding disorder,sever hypertension(systolic blood pressure over 180, diastolic blood pressure over 110),chronic kidney disease stage 3 or above,body mass index over35. Cases in which postoperative results could not be recorded.

Design outcomes

Primary

Measure	Time frame
pain at tourniquet infration is evaluated with a Visual Analogue Scale from 0 to 10 on postoperative day 1.	—

Secondary

Measure	Time frame
pain at the tourniquet infration on postoperative day 2 and 2 weeks,and wound pain on postoperative day 1, 2, and 2 weeks using the VAS. Leg swelling is evaluated by femoral and lower leg circumference on preoperative and postoperative day 1. Postoperative complications. Joint range of motion at 2 and 6 weeks postoperatively. Clinical scores at preoperative and 6 weeks postoperative are evaluated by questionnaire(knee injury and osteoarthritis score). Intraoperative and postoperative blood loss evaluated by blood sampling data.	—

Measure

Time frame

pain at the tourniquet infration on postoperative day 2 and 2 weeks,and wound pain on postoperative day 1, 2, and 2 weeks using the VAS. Leg swelling is evaluated by femoral and lower leg circumference on preoperative and postoperative day 1. Postoperative complications. Joint range of motion at 2 and 6 weeks postoperatively. Clinical scores at preoperative and 6 weeks postoperative are evaluated by questionnaire(knee injury and osteoarthritis score). Intraoperative and postoperative blood loss evaluated by blood sampling data.

—

Countries

Japan

Contacts

Public ContactTakayuki Nakayama

School of Medicine, Toho University (Ohashi) Ethics Committee Secretariat, Research Consultation Office

ohashi.rinri@ext.toho-u.ac.jp03-3468-1251

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026