The effect of cancer cachexia on vascular endothelial glycocalyx and body composition

The effect of cancer cachexia on vascular endothelial glycocalyx and body composition - The effect of cancer cachexia on vascular endothelial glycocalyx and body composition

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000049774

Enrollment

Registered

2022-12-15

Start date

2023-01-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer cachexia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Cancer patients aged 20 years or older who are admitted to the University of Yamanashi hospital between January 4, 2023 and December 31, 2024, and who request support from the palliative care team. (There are no restrictions on gender or upper age limit.) Patients diagnosed with cancer cachexia Diagnostic criteria is below. (1) Weight loss >5% in the past 6 months (2) BMI < 20, weight loss > 2% in the past 6 months (3) Sarcopenia, weight loss > 2% in the past 6 months ((1), (2), or (3) are met) Patients who can give written consent to participate in this study Patients who can communicate in Japanese

Exclusion criteria

Exclusion criteria: 1)Patients with serious cardiac or renal disease at the time of study enrollment 2)Patients with arteriovenous thrombosis 3)Patients with an implantable pacemaker 4)Patients with artificial limbs 5)Patients with a history of fatal arrhythmia 6)Patients who are judged by the physician to be ineligible

Design outcomes

Primary

Measure	Time frame
Differences in plasma syndecan-1 and heparan sulfate concentrations over time between the high PPI and low PPI groups	—

Countries

Japan

Contacts

Public ContactYasutomo Kumakura

University of Yamanashi Hospital Medical Team Center

ykurakuma@yamanashi.ac.jp055-273-1111

Outcome results