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Identifying Novel Sepsis Endotypes

Identifying Novel Pathophysiology-related Sepsis Endotypes: Exploratory Research - Endotype-sepsis study

Status
Recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000049747
Enrollment
1000
Registered
2022-12-12
Start date
2022-12-12
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

None listed

Sponsors

Division of Emergency and Critical Care Medicine, Tohoku University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients aged greater than or equal to 18 years old diagnosed as sepsis difined by Sepsis-3 diagnostic criteria.

Exclusion criteria

Exclusion criteria: 1. Patients who stay more than 24 hours at the previous hospital before transferring to to the participating hospital. 2. Patients who have sepsis after admission. 3. Patients who have cardiac arrest before obtaining the blood sample. 4. Patients or their legal representatives disagree with participating in the study.

Design outcomes

Primary

MeasureTime frame
Composite outcome of 28-day mortality and/or persistent organ dysfunction. Persistent organ dysfunction is an ongoing requirement for vasopressors, dialysis, or mechanical ventilation.—

Countries

Japan

Contacts

Public ContactDaisuke Kudo

Tohoku University Graduate School of Medicine Division of Emergency and Critical Care Medicine

kudodaisuke@med.tohoku.ac.jp022-717-7489

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026