Surgical site infection
Conditions
Interventions
1.5% oranexidine gluconate disinfection group
1% Chlorhexidine gluconate alcohol antiseptic
Sponsors
Keio University School
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients undergoing standby general anesthesia surgery in the field of digestive organs (esophagus, stomach, duodenum, small intestine, colon, liver, biliary tract, pancreas) with wound classification Class II 2) Patients must be at least 18 years of age at the time of obtaining research consent. 3) Written consent to participate in the study has been obtained from the patient
Exclusion criteria
Exclusion criteria: 1) Patients with a history of allergy to alcohol, including oranexidine gluconate or chlorhexidine gluconate alcohol 2) Patients who cannot be followed up for 30 days after surgery 3) Patients with active infection (except viral hepatitis) 4) Patients who have received antimicrobial agents the day before surgery 5) Emergency surgery and surgery requiring disinfection of mucous membrane surfaces and wound sites 6) Patients with a history of asthma 7) Other patients deemed by the physician to be unsuitable for the safe conduct of this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative 30-day surgical site infection rate | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative 30-day superficial incisional SSI rate, deep incisional SSI rate, organ/space SSI rate, positive bacterial wound culture rate, bacterial strain, intervention-related toxicity and allergic events rates, reoperation rate due to SSI, medical economic effect indicator, hospitalization duration. | — |
Countries
Japan
Contacts
Public ContactMasashi Takeuchi
Keio University School of Medicine Department of Surgery
Outcome results
None listed