Gingivitis
Conditions
Interventions
Ingest T0210 three times a day for 8wks.
Ingest placebo three times a day for 8wks.
Sponsors
Kao Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male and female aged 20-65 2. Those who have gingival inflammation that falls under any of the following A, B, or C A. When brushing your teeth, the gums may bleed. B. Gingiva may swell C. At dental offices and dental checkups, it has been pointed out that the gums are swollen and the periodontal pockets are deep.
Exclusion criteria
Exclusion criteria: (1) Those suffering from systemic diseases (diabetes, heart disease, kidney disease, liver disease, congenital heart disease, etc.) (2) Those who are taking drugs to improve glucose metabolism and lipid metabolism, or antihypertensive drugs (3) Those who plan to consume foods for specified health uses, foods with function claims, and dietary supplements (supplement foods such as capsules) that are considered to affect this study during the study period (which appeal to triglycerides, blood sugar, blood pressure, cholesterol, and body fat) (4) Those who have obvious trauma in the oral cavity (5) Those who are visiting a medical institution due to severe periodontal disease or oral disease (6) Those who have been prescribed antibiotics at a dental clinic due to gingival swelling within one year (7) Those who have had fever or respiratory symptoms in themselves or a family member living with them from one week before the measurement date, or those who have been in close contact with a person infected with the covid-19. (8) Those who use mouthwash on a daily basis (e.g., isodine mouthwash, clean mouthwash, gargle fresh, etc.) (9) Those who have collected 200 mL or more of blood (blood donation, etc.) within one month of the start of this study or 400 mL within three months. (10) Those who have severe anemia in the most recent medical examination (11) Those who have experienced side effects (feeling sick, dizziness, nausea, collapse, etc.) after blood collection (12) Those who have been allergic to sugar alcohols such as xylitol and erythritol in the past (13) Those who, for other reasons, are judged to be ineligible for the test by the dentist in charge of the trial or the director of the test and research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gingival condition before and after 8wks application | — |
Secondary
| Measure | Time frame |
|---|---|
| Ratio of specific bacteria in plaque | — |
Countries
Japan
Contacts
Public ContactTeppei Tajikara
Kao Corporation Personal Health Care Products Research Lab.
Outcome results
None listed