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Study on the effect of creatine /ergothioneine supplementation on sperm motility and in vitro fertilization

Study on the effect of creatine /ergothioneine supplementation on sperm motility and in vitro fertilization - Study on the effect of creatine /ergothioneine supplementation on sperm motility and in vitro fertilization

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000049691
Enrollment
100
Registered
2022-12-05
Start date
2022-12-06
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Adults

Interventions

Intake of 14g creatine/ergothionein supplement daily for 2 weeks

Sponsors

Kameda IVF Clinic Makuhari
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)Persons who received a sufficient explanation of the purpose and contents of the exam, have the capacity to consent, applied with free will with sufficient understanding, and agreed to participate with a written document 2)Healthy Japanese who are 20 years old 3)Sperm concentration over 5 million, sperm motility over 5% 4)Patients who visit an outpatient infertility clinic and are scheduled to undergo IVF

Exclusion criteria

Exclusion criteria: 1) Persons who have chronic diseases and are under medication, history of serious diseases, infectious diseases such as HIV, hepatitis B, hepatitis C, syphilis, etc. 2) Persons who are allergic to the test food 3)Persons who take test food daily before administration in this study 4) Those who have participated in other studies during one month prior to the start of the study, or who plan to participate in other studies after consenting to this study 5) Persons who were judged as inappropriate for study participants by the principal investigator

Design outcomes

Primary

MeasureTime frame
Semen volume, sperm count, and sperm motility

Secondary

MeasureTime frame
Sperm motility in automated analyzers(VAP,VSL,VCL,ALH) 8-OHdG, creatine, zinc, testosterone, and spermine levels in semen Fertilization rate, blastocyst delivery rate

Countries

Japan

Contacts

Public ContactTadashi Yoshimura

Healthcare Systems Co., Ltd. Sales and Planning Department

yoshimura@hc-sys.jp03-6809-2722

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026