Blood-brain barrier function assessed with MRI in cognitive deficits in neurological disorders

Blood-brain barrier function assessed with MRI in cognitive deficits in neurological disorders - Blood-brain barrier function assessed with MRI in cognitive deficits in neurological disorders

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000049624

Enrollment

250

Registered

2023-01-01

Start date

2023-02-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer disease, Dementia with Lewy bodies, Parkinson disease, Parkinsonism related disorders

Interventions

dynamic contrast-enhanced magnetic resonance imaging

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with Alzheimer disease, Dementia with Lewy bodies, Parkinson disease and Parkinsonism related disorders. Healthy volunteers.

Exclusion criteria

Exclusion criteria: Chronic and acute renal failure with eGFR less than 30 ml/min/1.73m2

Design outcomes

Primary

Measure	Time frame
blood-brain barrier function	—

Secondary

Measure	Time frame
Evaluation of cognitive function	—

Countries

Japan

Contacts

Public ContactNobukatsu Sawamoto

Kyoto University Hospital Department of Neurology

neuroofc@kuhp.kyoto-u.ac.jp075-751-3771

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026