Rehabilitations
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The preliminary study (exercise stimulus) at Kochi University is conducted with healthy subjects (20 years and older) who have never smoked. In addition, an exercise protocol (jump rope) is introduced and implemented, which was found to cause fluctuations in blood and saliva components in a preliminary literature review. Prof. Tatsuya Hisajima, Teikyo Heisei University, randomly selects healthy subjects over 20 years old who are undergo electroacupuncture stimulation, saliva collection before and after the stimulation, and a medical questionnaire. On the day of the session, the participants will undergo a health checkup, and then undergo electroacupuncture stimulation at the trigeminal nerve in the frontal lobe, saliva sampling, and a medical questionnaire.
Exclusion criteria
Exclusion criteria: 1.Those who are currently receiving drug treatment for any diseases (except for headache, common cold, etc.). 2.Those who are currently in the habit of taking or applying drugs. 3.Those who have hypersensitive scalp. 4. Those with a history or current history of hypertension, dyslipidemia, or diabetes mellitus. 5. Those with a history or current history of heart failure, renal failure, hepatitis B or hepatitis C 6. Those with a history or current history of serious disorders of the liver, kidneys, heart, lungs, blood, etc. 7. Those who sleep short hours (less than 5 hours a day) or long hours (more than 10 hours a day). 8. Those who have irregular or reversed day and night life due to work or part-time job. 9. Those with a BMI (kg/m2) of 30 or higher. 10. Those who drink more than 60g of alcohol/day on average on a daily basis. 11. Smokers. 12. Those who are likely to change their lifestyle during the study period (e.g., long trips, etc.). 13. Patients who need to take medication during the study period. 14. Currently participating in another human clinical trial, or not yet 3 months have passed since participation in another human clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This study searchs the indicator substances from salivary components (organic molecules, electrolytes, etc.) that show a strong correlation with cerebral blood flow, which fluctuates before and after acupuncture stimulation. | — |
Secondary
| Measure | Time frame |
|---|---|
| The explored indicator substances will be extensively examined from the viewpoints of neurology, physiology and immunology. | — |
Countries
Japan
Contacts
Kochi University Faculty of Science and Technology