patients who undergo general anesthesia
Conditions
Interventions
None listed
Sponsors
Shinshu University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: patient who underwent general anesthesia and was administrated ondansetron or droperidol intravenously in our institution during from October 1st, 2019 to September 30th, 2022
Exclusion criteria
Exclusion criteria: 1. patient who was administrated other drugs which affect QT interval (drugs which have description about prolongation of QT interval in Japan Pharmaceutical Reference) during from the start of general anesthesia to 30 min after the administration of target drug 2. patient who was administrated both ondansetron and droperidol during from the start of general anesthesia to 30 min after the administration of target drug 3. patient who was administrated target drug more than once 4. patient who was terminated the general anesthesia and the recording of patient monitor before the 30min after the administration of target drug
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| corrected QT interval about every 1 minute from 0 to 10 min and at 30 min after the administration of target drug | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. difference of corrected QT interval between the group of maintenance drug of general anesthesia 2. difference of corrected QT interval between the group of target drug 3. incidence of prolongation of corrected QT interval more than 10 ms 4. number of occurrence of postoperative nausea and vomiting | — |
Countries
Japan
Contacts
Public ContactKunihiro Mitsuzawa
Shinshu University School of Medicine The Department of Anesthesiology and Resuscitology
Outcome results
None listed