Research on Prevention and Improvement of Physical Frailty in the Elderly by Continuous Exercise and Intake of Nutritional Foods

A Double-Blind, Randomized, Placebo-controlled Trial on Prevention and Improvement of Physical Frailty in the Elderly by Continuous Exercise and Intake of Nutritional Foods - The Effect of Exercise and Nutritional Foods on Prevention and Improvement of Physical Frailty

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000049591

Enrollment

100

Registered

2022-11-22

Start date

2022-11-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Intake of placebo foods for 24 weeks Intake of nutritional foods for 24 weeks Intake of placebo foods and exercise for 24 weeks Intake of nutritional foods and exercise for 24 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Men and women over 70 years old. 2) Those who are pre-frail or frail according to J-CHS criteria.

Exclusion criteria

Exclusion criteria: 1) Patients who are currently in the hospital and have been restricted from exercising by their doctor, or who are unable to give their consent to participate in this study. 2) Patients who are judged to be unable to participate in the exercise intervention based on preliminary health status checks and preliminary examinations. 3) Those who are unable to give informed consent. 4) Those who exercise routinely. 5) Those who routinely consume medicines or health foods intended to improve motor function or muscle strength. 6) Those who take nutritional foods on a daily basis. 7) Those who are participating in other clinical trials. 8) Subjects who are allergic to foods.

Design outcomes

Primary

Measure	Time frame
Walking speed	—

Secondary

Measure	Time frame
Frailty Check Body composition Grip strength 30-second chair standing test (CS-30) Nutritional survey Physical activity Cognitive function	—

Countries

Japan

Contacts

Public ContactShuichi Machida

Juntendo University Graduate School of Health and Sports Science

machidas@juntendo.ac.jp0476-98-1001

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026