healthy person
Conditions
Interventions
Duration: 1 day Test food: Extract (low dose : 9 mg) Dosage: Take after the first saliva collection. 1 tablet, once a day.
Duration: 1 day Test food: Placebo Dosage: Take after the first saliva
Sponsors
Clinical Creative Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1 Age:Men and women between 20 and 60 years old (at the time of obtaining consent) 2 Admission/Foreign:Foreign 3 Healthy subjects (healthy subjects in this study are those who do not have any serious organ disorders or specific diseases, and who are not receiving any related treatment or any drug therapy. Whether or not a person qualifies as an able-bodied person is based on the person's declaration at the start of the examination). 4 Those who have 20 or more teeth as far as self-reporting is concerned. 5 Those who do not have oral diseases with treatment. 6 Those who is conscious of oral health 7 Persons who have given written consent to participate in the research
Exclusion criteria
Exclusion criteria: 1 Those taking medications that may affect the test results. 2 Persons with a history of hypersensitivity to grape dextrins 3 Persons who have a smoking habit 4 Those who have used antibiotics and antimicrobials within the past month. 5 Those who cannot abstain 5 from alcohol from the day before the examination. 6 Persons with diseases that may affect test results [epilepsy, diabetes, etc.], persons with systemic condition problems 7 Those who cannot eat or drink from the time they wake up until around 3:00 p.m. and cannot restrict oral care (gargling, brushing teeth, mouthwash, etc.) (only water can be consumed for a certain period of time). 8 Persons using Listerine or other antibacterial oral rinses during and prior to the study period 9 Those who regularly visit the dentist for oral care. 10 Those with dry mouth and low saliva production 11 Persons who habitually consume grape products (grapes, raisins, wine, 100% grape juice, etc.) 12 Persons using health foods, supplements, and medications that would affect this study 13 Pregnant or intending to become pregnant during the study period, or breastfeeding 14 Participation in another clinical trial within 3 months prior to obtaining consent or current participation in another clinical trial. 15 Persons for whom, in the judgment of the principal investigator or subinvestigator, the conduct of the study may increase the risk to the subject or may not provide sufficient data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral Bacteriology | — |
Countries
Japan
Contacts
Public ContactKazuhiro Ohno
Clinical Creative Co., Ltd. Pharmaceutical Development Division
Outcome results
None listed