Verification study on the effect of intake of test foods on skin barrier function

Verification study on the effect of intake of test foods on skin barrier function - Verification study on the effect of intake of test foods on skin barrier function

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000049525

Enrollment

200

Registered

2022-11-18

Start date

2022-11-19

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Daily intake of test food for 12 weeks Daily intake of placebo (control food) for 12 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy Japanese men and women who are 20 years of age or older at the time consent. 2. Who have dry skin. 3. Who have signed a consent form prior to the start of the study upon full explanation of the purpose and content of the study.

Exclusion criteria

Exclusion criteria: 1. Persons who are on treatment for a serious illness. 2. Persons with or treating skin disease. 3. Persons who can be expected to have hay fever during the study. 4. Persons who had procedures that may affect the study. 5. Persons with food allergies or those who may be allergic to the test food. 6. Persons who regularly use licensed drugs or quasi-drugs that may affect the study. 7. Persons who regularly use health foods that may affect the study. 8. Persons who are participating in a clinical trial or have participated in another clinical trial within 3 months from the date of obtaining consent. 9. Persons with excessive sunburn. 10. Persons who intentionally cannot refrain from exposure to direct sunlight during the study. 11. Smokers, or non-smokers who have not smoked within 3 months prior to the start of the study. 12. Persons who receive skin care treatments or use beauty devices daily. 13. Experience in cosmetic surgery. 14. Persons unable to maintain daily routines. 15. Pregnant, lactating, or wishing to become pregnant. 16. Persons who plan to participate in other examinations during the study. 17. Other subjects who are deemed inappropriate for this study by the investigator.

Design outcomes

Primary

Measure	Time frame
Transedermal water loss (TEWL)	—

Secondary

Measure	Time frame
Water content Elasticity Skin texture Skin wrinkles Skin tone Skin Surface Gloss Melanin Collagen Score Skindex-16 Likert Scale Questionnaire POMS2 d-ROMs BAP Simple OSP (urinary 8-OHdG/creatinine corrected, PAO) Oxidized LD	—

Countries

Japan

Contacts

Public ContactRyoko Koizumi

APO PLUS STATION CO., LTD. CRO Department Clinical Operations Division

food-contact@apoplus.co.jp03-6386-8809

Outcome results