RelatIonship between implementation of evidence-based and suppoRtive ICU care and outcomes of patients with acute respiratory distress syndrome

RelatIonship between implementation of evidence-based and suppoRtive ICU care and outcomes of patients with acute respiratory distress syndrome - The ICU LIBERATION study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000049507

Enrollment

1000

Registered

2022-12-01

Start date

2023-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients on an invasive or non-invasive ventilator within 24 hours of ICU admission 2) Patients who are expected to be on an invasive and/or non-invasive ventilator for more than 48 hours in total 3) Patients who meet the diagnosis of ARDS within 24 hours of ICU admission

Exclusion criteria

Exclusion criteria: 1) Patients who are younger than 16 years old 2) Patients with terminal conditions at the time of ICU admission 3) Patients who have been admitted to the ICU with a terminal care policy or who are expected to be admitted to the ICU with a terminal care policy within 24 hours of admission to the ICU 4) Patients who have expressed their refusal to have their clinical data used in research.

Design outcomes

Primary

Measure	Time frame
The following items will be collected in this study 1) Epidemiology: mortality (survival rate), length of ICU/hospital stay, mechanical ventilation period, etc. 2) Treatment: the achievement of lung-protective ventilation, mechanical ventilation setting, prone positioning, neuromuscular blockade, dialysis, etc. 3) Evidence-based ICU care 3-1) ABCDEF bundle implementation ratio 3-2) Evaluation of PADIS and its compliance status 3-3) Nutrition 3-4) ICU diary 3-5) The presence or absence of physical restraints 3-6) Sleep, etc.	—

Measure

Time frame

The following items will be collected in this study 1) Epidemiology: mortality (survival rate), length of ICU/hospital stay, mechanical ventilation period, etc. 2) Treatment: the achievement of lung-protective ventilation, mechanical ventilation setting, prone positioning, neuromuscular blockade, dialysis, etc. 3) Evidence-based ICU care 3-1) ABCDEF bundle implementation ratio 3-2) Evaluation of PADIS and its compliance status 3-3) Nutrition 3-4) ICU diary 3-5) The presence or absence of physical restraints 3-6) Sleep, etc.

—

Countries

Japan,Asia(except Japan),North America,South America,Australia,Europe,Africa

Contacts

Public ContactKeibun Liu

The Japanese Society for Early Mobilization LIBERATION Study Steering Committee

keiliu0406@gmail.com03-3556-5585

Outcome results