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Systematic Review and Meta-Analysis of Antithrombin Dosage for Patients with Septic DIC

Systematic Review and Meta-Analysis of Antithrombin Dosage for Patients with Septic DIC - Antithrombin for patients with septic DIC

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000049492
Enrollment
Unknown
Registered
2022-12-01
Start date
2022-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septic DIC

Interventions

None listed

Sponsors

Hokkaido University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Articles published until November 2022. Randomized controlled trials, retrospective analysis, and non-RCT, comparing antithrombin-treated and non-antithrombin-treated patients for septic DIC in adults. Patients; Adult patients diagnosed with Patients. Intervention; Antithrombin administration Comparison; Non-antithrombin administration Outcome; All-cause mortality, hemorrhagic complications, Withdrawal rate from the DIC

Exclusion criteria

Exclusion criteria: 1) Systematic review or meta-analysis articles, single prospective cohort study without a control group, case reports, repeated reports. 2) Literature of very low quality. 3) Studies with research purpose or operation type differed from those defined in this study. 4) Two investigators independently screened all titles, abstracts, and full texts for eligibility. Final inclusion will be decided after resolving discrepancies between the two investigators.

Design outcomes

Primary

MeasureTime frame
All-cause mortality

Secondary

MeasureTime frame
Hemorrhagic complications, Withdrawal rate from the DIC

Countries

Japan

Contacts

Public ContactTakumi Tsuchida

Hokkaido University Graduate School of Medicine Department of Anesthesiology and Critical Care Medicine

t.tsuchida@frontier.hokudai.ac.jp011-706-7377

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026