Effect of dialysis fluid on ECG and other biological responses

Effects of dialysis fluid on biological responses including ECG QTc - Dialysate QTc Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000049474

Enrollment

Registered

2022-12-01

Start date

2022-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-stage renal failure

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are currently attending or hospitalized at the hospital and are scheduled to change their dialysis solution, and who have given consent for the change of dialysis solution and for this study.

Exclusion criteria

Exclusion criteria: Patients with a previously prolonged QTc of >470 ms. Patients with atrial fibrillation. Patients taking digitalis. Patients who are minors.

Design outcomes

Primary

Measure	Time frame
Short-term cross-sectional study QTc changes with dialysate Long-term observational study Relationship between QT/C and change in each assessment point of electrolyte indices in blood	—

Secondary

Measure	Time frame
Short-term cross-sectional study Electrolyte (Mg, K, Ca) blood and dialysate concentration gradients in relation to QT/C and pulse rate Long-term observational study Relationship between changes in blood electrolyte indices at each endpoint and ABI, PWV, calcification index, events, and subjective symptoms	—

Countries

Japan

Contacts

Public ContactYASUYUKI MIMURA

Hyogo Medical University Hospital Cardiovascular and renal dialysis Internal Medicine

ya-mimura@hyo-med.ac.ip0798456521

Outcome results