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Comparison of medication persistence, adherence, and glycemic control among different administration frequencies for DPP-4 inhibitor in patients with type 2 diabetes: A retrospective cohort study of real-world data

Comparison of medication persistence, adherence, and glycemic control among different administration frequencies for DPP-4 inhibitor in patients with type 2 diabetes: A retrospective cohort study of real-world data - Comparison of medication persistence, adherence, and glycemic control among different administration frequencies for DPP-4 inhibitor in patients with type 2 diabetes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000049468
Enrollment
50000
Registered
2022-11-09
Start date
2022-11-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus

Interventions

None listed

Sponsors

Teijin Pharma Limited
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with type 2 diabetes who were prescribed DPP-4 inhibitors during the enrollment period (December 2016 - February 2019) 2. Patients who were prescribed DPP-4 inhibitor monotherapy on an outpatient basis from a single institution under the definition of type 2 diabetes on the index date (the date when prescription of DPP-4 inhibitors was started during the enrollment period) 3. Patients who had been consecutively registered in the database for at least 1 year before the index date (baseline period) 4. Patients who have been consecutively registered in the database for 1 year after the index date (follow-up period) 5. Patients over the age of 18 in the index month

Exclusion criteria

Exclusion criteria: 1. Patients who were designated as having type 1 diabetes during the baseline period 2. Patients who had been prescribed DPP-4 inhibitors (single drug or combination drug) during the baseline period

Design outcomes

Primary

MeasureTime frame
1. Medication persistence (the duration of time from initiation to discontinuation of therapy, the probability of medication persistence) 2. Medication adherence

Secondary

MeasureTime frame
Glycemic control

Countries

Japan

Contacts

Public ContactTetsuya Miwa

Teijin Pharma Limited Medical Science Department

tpm-com@umin.ac.jp03-3506-4140

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026