Gender differences in the relationship between TG/HDL-C ratio and metabolic syndrome

The ratio of triglyceride to high-density lipoprotein cholesterol in females may be a better indicator of metabolic syndrome and its components than in males in a Japanese population - Gender differences in the relationship between TG/HDL-C ratio and metabolic syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000049445

Enrollment

10000

Registered

2022-11-08

Start date

2022-11-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic syndrome

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Among 11,673 Japanese subjects who had undergone an annual health check-up between April 2019 and March 2020 at the Health Planning Center of Nihon University Hospital, 10,373 subjects (females, 4,056; males, 6,317) were recruited for this study.

Exclusion criteria

Exclusion criteria: The exclusion criteria included refusal to provide consent for participation in the study, current lipid-modified, treatment, and diagnosis of cerebral and/or cardiovascular disease, serum triglyceride levels more than 400mg/dL, and no measurement of abdominal circumference and serum lipid level.

Design outcomes

Primary

Measure	Time frame
The primary efficacy parameter was the relationship between the TG/HDL-C ratio and abdominal obesity by gender.	—

Secondary

Measure	Time frame
The secondary endpoint was the relationship between the TG/HDL-C ratio and the prevalence of Mets and its components as cardio-metabolic risk by gender.	—

Countries

Japan

Contacts

Public ContactShigemasa Tani

Nihon University Hospital Health Planning Center

tani.shigemasa@nihon-u.ac.jp0332931711

Outcome results