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Pathophysiology of chronic constipation of anorectal outlet obstruction using rapid barostat bag test, anorectal manometry and rectal mucosa biopsy samples.

Pathophysiology of chronic constipation of anorectal outlet obstruction using rapid barostat bag test, anorectal manometry and rectal mucosa biopsy samples. - Pathophysiology of chronic constipation of anorectal outlet obstruction.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000049376
Enrollment
50
Registered
2022-11-01
Start date
2023-01-19
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic constipation

Interventions

Patients with chronic constipation who have been diagnosed with functional constipation by lower gastrointestinal endoscopy and biopsy tissue diagnosis, as organic constipation is considered necessary

Sponsors

Kyushu University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with chronic constipation by March 31, 2027 who have been diagnosed with functional constipation by lower gastrointestinal endoscopy and biopsy tissue diagnosis, as organic constipation is considered necessary to exclude.

Exclusion criteria

Exclusion criteria: (1) Patients with warning signs such as vomiting, gastrointestinal bleeding (including findings of hematemesis, hemorrhage, and anemia), or rapid weight loss (2) Patients with other factors (comorbidities or history of surgery) that may affect the results of rapid barostat bag test or anorectal manometry (3) Patients with serious organ damage or concomitant psychiatric disorders (4) Patients with confirmed or suspected malignant lesions (5) Pregnant women, lactating women, or women who may be pregnant (6) Other patients deemed inappropriate for this study by the attending physician

Design outcomes

Primary

MeasureTime frame
Relationship between severity of functional constipation and intestinal perception and anal sphincter function.

Countries

Japan

Contacts

Public ContactYoshimasa Tanaka

Kyushu University Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences

tanaka.yoshimasa.997@m.kyushu-u.ac.jp+81-92-642-5286

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026