food allergy
Conditions
Interventions
Slow low dose oral immunotherapy (ingesting hen'
s egg, cow milk and wheat protein everyday with increasing the dose at home whenever they could for every 30 consecutive intakes without obviouslious allergic symptoms)
complete avoidance of antigen
Sponsors
Department of Pediatrics, Shimane University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Diagnosed with FA of either egg, milk, or wheat. 2) Less than 16 years of age at the time of consent. 3) Weighs 15 kg or more and is able to possess epinephrine autoinjector. 4) Positive oral food challenge with less than 3.5 g of boiled egg white or udon noodles or less than 3.5 mL of cow's milk. 5) Written consent to participate in the study has been obtained from the parents.
Exclusion criteria
Exclusion criteria: 1) severe anaphylaxis induced by oral food challenge 2) uncontrolled bronchial asthma or atopic dermatitis 3) Has malignancy, autoimmune disease, immunodeficiency, severe cardiac disease, or chronic infectious disease 4) Consecutive use of systemic corticosteroids or anticancer agents 5) Undergoing other immunotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The result of oral food challenges after one-year of Shimane-SLOIT | — |
Secondary
| Measure | Time frame |
|---|---|
| safety of Shimane-SLOIT | — |
Countries
Japan
Contacts
Public ContactSeiya Masukane
Shimane University School of Medicine Department of Pediatrics
Outcome results
None listed