Evaluation of amygdala activity using PET CT for risk assessment and prevention of lethal arrhythmias

Evaluation of amygdala activity using PET CT for risk assessment and prevention of lethal arrhythmias - PET-ICD

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000049333

Enrollment

Registered

2022-10-26

Start date

2023-03-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

VT/VF

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients implanted with ICD/CRT-D for prevention of VT/VF development associated with organic heart disease

Exclusion criteria

Exclusion criteria: Patients who are determined to be incapable of PET-CT imaging due to a serious disease Patients with substance-related disorders Patients with severe claustrophobia Pregnant, possibly pregnant, or lactating patients Patients who are deemed by the physician to be unsuitable for the study

Design outcomes

Primary

Measure	Time frame
Relationship between amygdala activity and VT/VF onset	—

Secondary

Measure	Time frame
Correlation between amygdala activity and total number of Af burden during the observation period Correlation between amygdala activity and number of VPC/NSVT Correlation between amygdala activity and mean nocturnal heart rate Correlation between amygdala activity and presence of heart failure requiring hospitalization Correlation between amygdala activity and stress tolerance	—

Countries

Japan

Contacts

Public ContactSou Otsuki

Niigata University School of Medical and Dental Sciences Department of Cardiovascular Medicine

tallmoca_0825@yahoo.co.jp0252272185

Outcome results