Intermediate-size (10-20 mm) sessile colorectal lesions
Conditions
Interventions
Conventional EMR Group needle injection of normal saline into the submucosa and snare resection of the lesion
Underwater EMR(UEMR) Group immersion of the entire lumen in water and snare resection of
Sponsors
Osaka International Cancer Institute
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with intermediate-size (10-20 mm) sessile colorectal lesions who can register one lesion on the most proximal side and undergo endoscopic resection. 2.Patients who can be followed from endoscopic resection to follow up colonoscopy. 3.Patients without colorectal neoplastic lesions requiring surgical resection. 4.Patients who are at least 20 years old at enrollment. 5.Patients who have written informed consent from themthelves or a surrogate.
Exclusion criteria
Exclusion criteria: 1.Patients previously enrolled in the study. 2.Lesions suspected of residual recurrence 3.Patients with significant electrolyte (Na, Cl) abnormalities 4.Patients with inflammatory bowel disease and polyposis coli 5.Other patients deemed unsuitable for safe treatment by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of locoregional recurrences after one year of endoscopic treatment in all enrolled cases | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of recurrence-free after endoscopic treatment in all eligible cases Proportion of en bloc resection Proportion of histologically complete resection Proportion of endoscopically complete resection Proportion of adverse events Procedure time | — |
Countries
Japan
Contacts
Public ContactTakeshi Yamashina
Kansai Medical University Medical Center 3-1-69, Otemae, Chuo-ku, Osaka
Outcome results
None listed