Usefulness of oral probiotics for chronic constipation and its effect on intestinal flora and systemic immunity in the elderly

A study on the usefulness of oral probiotics for chronic constipation and its effect on intestinal flora and systemic immunity in the elderly - A study on intestinal bacteria and systemic immunity in chronic constipation in the elderly

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000049271

Enrollment

100

Registered

2022-10-20

Start date

2020-08-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic constipation

Interventions

Laxative and Lactobacillary preparation (Interventions) Laxative only/ (Control)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged 65 or older, who have ruled out organic disease in the large intestine by colonoscopy, and who have consented to the deposit of specimens in the biobank

Exclusion criteria

Exclusion criteria: The patient who can't obtain consent to the research participation, and who a physician in charge judges an inadequacy are excluded

Design outcomes

Primary

Measure	Time frame
Comparison about respoded rate of the improvement of the voluntary evacuation	—

Secondary

Measure	Time frame
Comparison regarding quantitative evaluation of intestinal microbiota and systemic immune competence	—

Countries

Japan

Contacts

Public ContactYoshiko Suzuki

National Center for Geriatrics and Gerontolog Department of Gastroenterology

matsuura@ncgg.go.jp0562-46-2311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026