Glaucoma
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Disease name:Open-angle glaucoma patients, cataract patients 2.Stage:early to middle stage 3.Age:50 years old or older, 85 years old or younger(at the time of registration) 4.Gender:Regardless of gender
Exclusion criteria
Exclusion criteria: 1.Those who have severe dysphagia and have difficulty taking curcumin supplements 2.Alcohol addiction, drug addiction patients 3.Those who cannot follow the protocol of this study such as oral administration and fundus examination due to severe cognitive decline. 4.Those who have been administered corticosteroids within 1 month 5.Those with gallbladder disease, gallstones, gastrointestinal disorders 6.Those who have been diagnosed with angle-closure glaucoma and have difficulty in mydriasis 7.Those who cannot perform visual field test or OCT, those who have difficulty in fundus examination and cannot see through the fundus with SLO 8.Those who have severe vision loss (need assistance in daily life due to visual impairment) 9.Those who are judged by the principal investigator or research coordinator to be unsuitable for participation in the research 10.Pregnant women, lactating women, those who wish to become pregnant during the research period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences between glaucoma patients, cataract patients and healthy subjects regarding the parameters obtained by retinal amyloid imaging | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between parameters acquired by retinal amyloid imaging and cognitive function according to glaucoma severity (glaucoma subgroup analysis) | — |
Countries
Japan
Contacts
Tohoku University Graduate School of Medicine Department of Ophthalmology