Skip to content

Exercise therapy for rheumatoid arthritis patients tapering molecular targeted therapies.

The effect of personalized exercise therapy on disease activity of rheumatoid arthritis patients who achieved remission or low disease activity and started tapering molecular targeted therapies: a randomized controlled pilot study. - Exercise therapy for rheumatoid arthritis patients tapering molecular targeted therapies.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000049223
Enrollment
30
Registered
2022-10-17
Start date
2022-10-19
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rheumatoid arthritis

Interventions

Personalized Exercise therapy: load exercise 3 times a week for 30 minutes. The strength of the exercise are personally adjusted by Borg scale. Control

Sponsors

Osaka Metropolitan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with rheumatoid arthritis who achieved remission or low disease activity with regular dose of molecular targeted therapies (b-DMARDs or ts-DMARDs) and initiated tapering molecular targeted therapies (dose reduction or spacing) within 3 months before the informed consent. Patients who can attend the hospital regularly. Patients who can read and understand Japanese language. Patients who provide a written informed consent for this study.

Exclusion criteria

Exclusion criteria: Patients who cannot stand or walk. Patients who are not allow to do exercise by the physician. Patients who have cognitive impairment. Patients for whom physicians judge as inappropriate to join this study

Design outcomes

Primary

MeasureTime frame
Disease activity of rheumatoid arthritis 16 weeks after the intervention.

Secondary

MeasureTime frame
Maintenance rate of remission or low disease activity with tapered dose of molecular targeted therapies 16 weeks after the intervention. QOL of RA patients 16 weeks after the intervention.

Countries

Japan

Contacts

Public ContactMOTOMU HASHIMOTO

Osaka Metropolitan University Department of Clinical Immunology

motomu.hashimoto@omu.ac.jp06-6645-3981

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026