Healthy subjects
Conditions
Interventions
4 weeks intake of the test food 1
4 weeks intake of the test food 2
Sponsors
ITO EN, Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Age in the range of 20 to < 60 2) Non smokers 3) Healthy men and women
Exclusion criteria
Exclusion criteria: 1) Subject who is currently receiving any medications or outpatient treatment 2) Subjects who are currently going to the dentist for reasons other than regular health checkups such as dental caries and periodontal disease 3) Subjects who regularly use foods and medicines that can be expected to improve the oral flora and oral environment 4) Subject who is may develop allergy due to the test food 5) Subject who is pregnant, breast-feeding, or willing to become pregnant during the study period 6) Subjects currently participating in other clinical trials or willing to participate in other clinical trials during the study period 7) Other than the above, subjects who are judged to be ineligible for this study by the principal investigator or the study supervisor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) Number and ratio of periodontal disease-related bacteria in saliva 2) Number and ratio of caries-related bacteria in saliva | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Change in the number and ratio of periodontal disease-related bacteria in saliva 2) Change in the number and ratio of caries-related bacteria in saliva 3) Total number of bacteria in saliva and its change 4) Salivary pH and its change 5) Oral moisture level and its change | — |
Countries
Japan
Contacts
Public ContactYasushi Tanaka
ITO EN, Ltd. Central Research Institute
Outcome results
None listed