Healthy female adults
Conditions
Interventions
Inhalation of a test odorant-containing tap-water mist (100 mL), which is emitted from an aroma-diffuser, to the subject at her normal bedtime for four weeks.
Inhalation of a deionized water-containin
Sponsors
CPCC Company Limited
Graduate School of Integrative and Global Majors, Tsukuba University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1) Healthy female subjects ranging in age from 30 to 44, at informed consent. (2) Subjects who feel pretty stress, skin dryness, and skin tension. (3) Subjects not being poor at a sweet-smelling citrus (kabosu). (4) Subjects equipped with a capacity to breath in the odorant from the diffuser, being at home. (5) Subjects who can give informed consent to partake in this trial after being provided with an explanation of the protocol detail.
Exclusion criteria
Exclusion criteria: (1) Subjects who take steadily (not less than three times a week) in the health-specific/functional/supplementary (e.g., gamma-aminobutyric acid, glucosylceramide, sodium hyaluronate, L-theanine)/health foods, which might affect the test results. (2) Subjects who have taken affecting medicines (e.g., skin roughness-improving drug, and sleeping pill), and have any difficulty in refraining from taking them during this trial. (3) Subjects with the condition of being over-sensitiveness to cold, even during the summer season. (4) Subjects who realized that the subjects themselves must be in a state of menopausal symptom. (5) Subjects with nasal congestion and/or wrong judgement of fragrance. (6) Subjects falling into the habit of smoking within one year before this trial. (7) Subjects having a bruise and/or a hurt near the skin-measuring position (left cheek part). (8) Subjects having their skin roughness due to pollinosis, during this trial. (9) Subjects with excessive suntan, and/or some kind of work/sport outside for a long time. (10) Subjects who are possible to go on a trip, and/or a business one during this trial, which might affect the test-device usage. (11) Subjects who are now under a specific facial care (e.g., facial/body treatment, electric facial, peeling, laser therapy, and hair removal) at an outside agency. (12) Subjects who have previous/current medical history of severe cardiac, hepatic, renal or digestive diseases. (13) Pregnant, lactating women, or possibly pregnant ones. (14) Subjects suffering from atopic/contact dermatitis, and skin hypersensitivity. (15) Subjects who are now under other clinical tests with some kind of medicine and/or health food, or partook in those within four weeks before this trial, or are planning to participate in those after giving informed consent to take part in this trial. (16) Others who have been determined as ineligible for participation, judging from the investigator's opinions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stratum corneum water-binding capacity, and skin viscoelasticity | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. VISIA TM Evolution (blotch, wrinkle, texture, pores, ultraviolet-blotch, brownish blotch, reddish blotch, porphyrin) 2. Blood-flow volume 3. Stress Check List 30 4. Multiple measurements of emotion using a multiple mood scale (40 questions) 5. Skin questionnaire 6. Pittsburgh Sleep Quality Index 7. Oguri-Shirakawa-Azumi sleep inventory ver. MA | — |
Countries
Japan
Contacts
Public ContactMasanori Numa
CPCC Company Limited Clinical Planning Department
Outcome results
None listed