Investigation of the effect of ischemic preconditioning in CLTI patients using quantitative lower extremity arteriography.

Investigation of the effect of ischemic preconditioning in CLTI patients using quantitative lower extremity arteriography. - Investigation of the effect of ischemic preconditioning in CLTI patients using quantitative lower extremity arteriography.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000049175

Enrollment

Registered

2022-10-14

Start date

2022-10-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic limb-threatening ischemia

Interventions

DSA and 2DP angiography will be performed on the below-knee artery in CLTI patients. The lower leg is then compressed with a manchette at a pressure of 200 mmHg for 5 minutes and then released for 5 m

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: This study will include CLTI patients undergoing EVT to the below-knee artery at Toho University Medical Center Omori Hospital. If the patient has lesions in the iliac or femoral arteries, measurements will be taken at the time of EVT for the below-knee artery after EVT for the iliac and femoral arteries is performed.

Exclusion criteria

Exclusion criteria: Consent cannot be obtained in cases of inadequate judgment or unconsciousness, and therefore will not be included in this study.

Design outcomes

Primary

Measure	Time frame
DSA and 2DP angiography will be performed on the arteries below the knee in patients with CLTI. The lower leg will then be compressed with a manchette at a pressure of 200 mmHg for 5 minutes and then released for 5 minutes. 5 minutes of compression and release will be considered as one set, and DSA and 2DP angiography will be performed again after two sets to determine whether improvement in lower extremity blood flow is achieved.	—

Measure

Time frame

DSA and 2DP angiography will be performed on the arteries below the knee in patients with CLTI. The lower leg will then be compressed with a manchette at a pressure of 200 mmHg for 5 minutes and then released for 5 minutes. 5 minutes of compression and release will be considered as one set, and DSA and 2DP angiography will be performed again after two sets to determine whether improvement in lower extremity blood flow is achieved.

—

Countries

Japan

Contacts

Public ContactRyota Noike

Department of internal medicine, Toho university faculty of medicine cardiovascular medicine

ryouta.noike@med.toho-u.ac.jp03-3762-4151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026