chronic pain
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients 1) Patients who visit the pain clinic, Department of Anesthesiology, Okayama University Hospital after ethics committee approval to March 31, 2024. 2) Patients who consent to voluntary participate in writing. 3) Patients aged 20 to 90 years at the time of informed consent. Healthy participants 1) Those who have no pain lasting more than 3 months. 2) Those who are able to obtain written consent from the individual to participate in the research voluntarily. 3) Those who are 20 years old or older and under 90 years old at the time of obtaining consent.
Exclusion criteria
Exclusion criteria: 1) Women who are pregnant or may become pregnant 2) Cancer pain 3) Acute cerebral infarction, acute myocardial infarction, cerebral hemorrhage 4) In addition, patients considered to be inappropriate for the study, the study doesn't benefit for participants, the case that plan evaluation is prevented, limited, or confused, participants are family member of employee, principal investigator, or co-investigator, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of plasma HMGB1 level and pain intensity (VAS/BPI) | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma levels (oxytocin, cortisol, cystatin C), psychological evaluation (HADS/PCS), EQ-5D (QOL questionnaire) | — |
Countries
Japan
Contacts
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Anesthesiology and Resuscitology